Journal Guide

Protein & Cell publishes original research articles, reviews, and commentaries concerning the latest developments in multidisciplinary areas in biology and biomedicine, with an emphasis on protein and cell research. Subject areas include biochemistry/biophysics, cell biology, developmental biology, genetics, immunology, microbiology, molecular biology, neuroscience, oncology, protein science, structural biology and translational medicine. In addition, Protein & Cell addresses research highlights, news and views, and commentaries covering research policies and funding trends in China, and provides a forum to foster academic exchange among researchers across different fields of the life sciences.

Protein & Peptide Letters publishes letters, original research papers, mini-reviews and guest edited issues in all important aspects of protein and peptide research, including structural studies, advances in recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, and drug design. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallization and preliminary structure determination of biologically important proteins are considered only if they include significant new approaches or deal with proteins of immediate importance, and preliminary structure determinations of biologically important proteins. Purely theoretical/review papers should provide new insight into the principles of protein/peptide structure and function. Manuscripts describing computational work should include some experimental data to provide confirmation of the results of calculations

A Community-Based Journal for Protein ScientistsIn January 2004, the journal Protein Engineering was relaunched as Protein Engineering, Design and Selection, or PEDS. PEDS publishes research papers and review articles relevant to the engineering, design and selection of proteins for use in biotechnology and therapy, and for understanding fundamental properties of activity, stability, folding, misfolding and disease. The journal has new editors, a new editorial structure, and a new reviewing system to make it a community journal run by protein scientists for their own discipline.

The power of modern molecular genetics to provide large quantities of proteins that were previously difficult to obtain has sparked an explosion of interest in both practical and theoretical aspects of protein purification.Protein Expression and Purification is dedicated to providing a forum for information about protein isolation based on conventional fractionation as well as techniques employing various molecular biological procedures to increase protein expression.The following types of articles are published:• Original articles reporting novel or significantly improved isolations of highly purified proteins• Procedures for expressing and isolating proteins from genetically engineered sources• Novel or improved molecular biological methods for overexpression of specific proteins• Review articles that describe and evaluate important approaches to the expression and purification of proteins

Protein Science serves as an international forum for publishing original reports on proteins in the broadest sense. The Journal aims to unify this field by cutting across established disciplinary lines and focusing on #!#!protein-centered#!#! science.

PROTEINS : Structure, Function, and Bioinformatics publishes original reports of significant experimental and analytic research in all areas of protein research: structure, function, computation, genetics, and design. The journal encourages reports that present new experimental or computational approaches for interpreting and understanding data from biophysical chemistry, structural studies of proteins and macromolecular assemblies, alterations of protein structure and function engineered through techniques of molecular biology and genetics, functional analyses under physiologic conditions, as well as the interactions of proteins with receptors, nucleic acids, or other specific ligands or substrates. Research in protein and peptide biochemistry directed toward synthesizing or characterizing molecules that simulate aspects of the activity of proteins, or that act as inhibitors of protein function, is also within the scope of PROTEINS. In addition to full-length reports, short communications (usually not more than 4 printed pages) and prediction reports are welcome. Reviews are typically by invitation; authors are encouraged to submit proposed topics for consideration. Proteins is bringing web-based technology to bear to speed and simplify the entire publication process. Proteins now offers online submission and peer review and encourages electronic submission of manuscripts, which expedites the review process. In addition, individual articles are published online as rapidly as possible after acceptance. Please see the Author Instructions for details. Proteins is pleased to announce that online access to the full-text content of all Structure Notes is freely available to all nonsubscribing users , commencing 2003. Structure Notes, first launched in 1999, are one-to-two-page articles describing a novel protein structure of unknown function and/or those with recurring topology. Structure Notes are published within three months of receipt at the Proteins office by expediting all stages of editorial review and production. Please see the Author Instructions for details.

Proteome Science is ready to receive manuscripts based on all aspects of functional and structural proteomics.

Proteomes (ISSN 2227-7382) is an open access, peer reviewed journal on all aspects of proteome science. Proteomes covers the multi-disciplinary topics of structural and functional biology, protein chemistry, cell biology, methodology used for protein analysis, including mass spectrometry, protein arrays, bioinformatics, HTS assays, etc. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on the length of papers.

PROTEOMICS - Clinical Applications has developed into a key source of information in the field of applying proteomics to the study of human disease and translation to the clinic. With 12 issues per year, the journal will publish papers in all relevant areas including: basic proteomic research designed to further understand the molecular mechanisms underlying dysfunction in human disease the results of proteomic studies dedicated to the discovery and validation of diagnostic and prognostic disease biomarkers the use of proteomics for the discovery of novel drug targets the application of proteomics in the drug development pipeline the use of proteomics as a component of clinical trials.