Fluctuation and Noise Letters (FNL) is unique. It is the only specialist journal for fluctuations and noise, and it covers that topic throughout the whole of science in a completely interdisciplinary way. High standards of refereeing and editorial judgment are guaranteed by the selection of Editors from among the leading scientists of the field.FNL places equal emphasis on both fundamental and applied science and the name "Letters" is to indicate speed of publication, rather than a limitation on the lengths of papers. The journal has recently moved to on-line submission and immediate on-line publication of accepted papers.FNL is interested in interdisciplinary articles on random fluctuations, quite generally. For example: noise enhanced phenomena including stochastic resonance; 1/f noise; shot noise; fluctuation-dissipation; cardiovascular dynamics; ion channels; single molecules; neural systems; quantum fluctuations; quantum computation; classical and quantum information; statistical physics; degradation and aging phenomena; percolation systems; fluctuations in social systems; traffic; the stockmarket; environment and climate; etc.FNL also encourages open public debate. Scientists with critical views about important results published in high-profile journals and magazines are encouraged to submit a comment or note to FNL. These papers are published with an accelerated editorial procedure to facilitate lively debate in the field.